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BioKin, Ltd. www.biokin.com/index.html About Us www.biokin.com/about.html Program DynaFit Analysis of (bio)chemical kinetics and equilibria www.biokin.com/dynafit/index.html DynaFit Manual Documentation for program DynaFit www.biokin.com/dynafit/manual.html Download DynaFit Download the program DynaFit for the analysis of (bio)chemical kinetics and equilibria www.biokin.com/dynafit/download.html DynaFit under Linux Mint Instructions to install and test DynaFit under Linux Mint 16 www.biokin.com/dynafit/linuxmint.html Bibliography Research papers in which DynaFit was used for the analysis of experimental data. www.biokin.com/dynafit/bibliography.html DynaFit License Request a DynaFit license www.biokin.com/dynafit/license/index.html Request Academic License For DynaFit users affilitated with educational organizations only www.biokin.com/dynafit/license/academic.html Request Commercial License For DynaFit users affilitated with for-profit organizations www.biokin.com/dynafit/license/commercial.html Consulting Services Data analysis in chemistry, biology, biochemistry, and related fields www.biokin.com/consulting/index.html Sample Contract #1 Consulting and custom software development www.biokin.com/consulting/sample1.html Sample Contract #2 Consulting and custom software development www.biokin.com/consulting/sample2.html Sample Contract #3 Consulting and custom software development www.biokin.com/consulting/sample3.html Sample Contractor Agreement Consulting and custom software development www.biokin.com/consulting/sample4.html BioKin Publications Journal articles and technical reports www.biokin.com/publications/index.html Journal Articles Journal articles and book chapters www.biokin.com/publications/articles.html Technical Reports Longer or highly focussed research reports www.biokin.com/publications/techreports.html Technical Notes Shorter notes on technical subjects www.biokin.com/publications/technotes/index.html History of the "Morrison Equation" History, variants and usage of the "Morrison equation" in enzyme inhibition kinetics www.biokin.com/publications/technotes/TN201501.html EGFR inhibition: Ki and kinact Determination of inhibition constants (Ki) and inactivation rate constants (kinact) www.biokin.com/publications/technotes/TN201502.html King-Altman method in DynaFit DynaFit was updated to derive "kinetic constants" (Michaelis constants etc.) www.biokin.com/publications/technotes/TN201503.html An algebraic model for covalent inhibition kinetics Preprint www.biokin.com/publications/technotes/TN201504.html Substrate kinetics from reaction progress DynaFit tutorial www.biokin.com/publications/technotes/TN201505.html Time-dependent inhibition of 5alpha-steroid reductase DynaFit tutorial www.biokin.com/publications/technotes/TN201506.html Integrated Michaelis-Menten equation in DynaFit. Part 1. Determination of substrate kinetic parameters of EGFR kinase www.biokin.com/publications/technotes/TN201601.html Integrated Michaelis-Menten equation in DynaFit. Part 2. Determination of substrate kinetic parameters of 5alpha-ketosteroid reductase www.biokin.com/publications/technotes/TN201602.html Integrated Michaelis-Menten equation in DynaFit. Part 3. Determination of substrate kinetic parameters of HIV protease www.biokin.com/publications/technotes/TN201603.html Lectures and Seminars www.biokin.com/lectures.html Lecture Courses and Workshops www.biokin.com/courses/index.html Brno 2014: Binding and Kinetics for Experimental Biologists Masaryk University | Department of Experimental Biology | May, 12-16 2014 www.biokin.com/courses/BKEB/index.html Course Syllabus Organization details www.biokin.com/courses/BKEB/syllabus.html Course Lectures Copies of PowerPoint slides www.biokin.com/courses/BKEB/lectures.html London 2014: Binding Constants and Mechanisms Biochemical Society (U.K.) | May 2, 2014 www.biokin.com/courses/london2014/index.html Training Day Organisation Monday - May 2, 2014 www.biokin.com/courses/london2014/organisation.html Training Day Lectures Copies of PowerPoint slides www.biokin.com/courses/london2014/lectures.html Preloaded Software Package Download DynaFit with a 30-day license for Training Day delegates www.biokin.com/courses/london2014/software.html Tools Basic tools for statistical data analysis: standard deviation, F-statistics, and more. www.biokin.com/tools/index.html Optimal Design of Experiments For dose-response inhibitor screening www.biokin.com/tools/design.html Average and Standard Deviation Including Student t confidence intervals www.biokin.com/tools/average.html Critical values of F-Statistics An on-line statistical calculator www.biokin.com/tools/f-critical.html Nested models Statistical calculator for model discrimination analysis www.biokin.com/tools/nestedmodels.html Two treatment groups Statistical calculator for the difference in two treatment groups www.biokin.com/tools/twogroups.html Kinetics with MAPLE Generate MAPLE code for deriving simple rate laws www.biokin.com/tools/maplekin.html Kinetics with Mathematica Generate Mathematica code for deriving simple rate laws www.biokin.com/tools/mathekin.html King-Altman Method Analysis of steady-state enzyme kinetics www.biokin.com/tools/king-altman/index.html Submit Data Derivation of steady-state rate equations using the King-Altman method www.biokin.com/tools/king-altman/submit.html Example Problems Derivation of steady-state rate equations using the King-Altman method www.biokin.com/tools/king-altman/examples.html Theoretical Notes Derivation of steady-state rate equations using the King-Altman method www.biokin.com/tools/king-altman/theory.html Enzyme Inhibitor Potency Grouping of enzyme inhibitors into tiers of (nearly) identical potency www.biokin.com/tools/potency/index.html Submit Data Grouping of enzyme inhibitors into tiers of (nearly) identical potency www.biokin.com/tools/potency/submit.html Example Problems Grouping of enzyme inhibitors into tiers of (nearly) identical potency www.biokin.com/tools/potency/examples.html Theoretical Notes Grouping of enzyme inhibitors into tiers of (nearly) identical potency www.biokin.com/tools/potency/theory.html Site map A listing of all files that comprise this web site. www.biokin.com/sitemap.html Contact Information Contact information for BioKin Ltd. www.biokin.com/contact.html
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