BioKin, Ltd. - Technical notes: King-Altman method in DynaFit

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TN201503

King-Altman method in DynaFit

DynaFit was updated to derive "kinetic constants" (Michaelis constants etc.)

Implementation of the King-Altman method in DynaFit

BioKin Technical Note TN-2015-03

Petr Kuzmic
BioKin Ltd.
Draft - Rev. 1.01 - April 3, 2015

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Abstract

The DynaFit software package was updated to enable the automatic derivation of Michaelis constants, turnover numbers, and inhibition constants for reagents (substrate and products) as well as external ligands (inhibitors and activators). An illustrative example includes the derivation of kinetic constants for the “Ordered Bi Bi” kinetic mechanism [Segel, I. (1975) Enzyme Kinetics, p. 560-564].

Keywords

steady-state; enzyme kinetics; mathematics; bisubstrate mechanisms; King-Altman

How to Cite

Kuzmic, P. (2015) Implementation of the King-Altman method in DynaFit, BioKin Technical Note TN-2015-03, BioKin Ltd., Watertown MA, [Online] www.biokin.com/TN/2015/03

Download Example Script

Download ~3 kB

After downloading the ZIP archive file, extract the entire package into the DynaFit main installation directory.

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Thu May 16 16:21:32 2024