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Derivation of steady-state rate equations using the King-Altman method |
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[May 2015]
- A significantly enhanced version of this online tool
was made part of the software package DynaFit.
- See BioKin Technical Note TN-2015-03 for details.
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After submitting the form, select Return in your browser to return to this page.
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Type your mechanism using the following rules:
- In the [mechanism] section, use double-sided arrows (<==>) to represent bi-directional steps, associated with two rate constants (forward and reverse).
- Use single-sided arrows (-->), pointing always from left to right, to represent uni-directional steps.
- List each step (uni- or bi-directional) on a separate line.
- Reaction arrows can be represented by using an arbitrary number of dashes (e.g., ->, --->, <====>)
- Molecule names are completely arbitrary (e.g., for the enzyme substrate complex: ES, E.S, Enzyme-Substrate, XYZ)
- In the [modifier] section, type a list of inhibitors and/or activators separated by commas.
- All modifiers (inhibitors and/or activators) must be listed in their special section, otherwise the derivation fails.
- Reordering reaction steps will change the order (numbering) of rate constants.
- Everything to the right of a semicolon (;) is ignored as a comment.
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www.biokin.com/tools/king-altman/submit.html Thu May 16 16:21:32 2024 |