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Course Syllabus
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Official Course Site: Masaryk University Brno, CZ


Time and PlaceTop of pageNext section
  • The course IC113 meets in the seminar room 1.21 in building A2 at 9:00.
  • The curriculum includes two 50-minute lectures each morning.
  • After lunch break we meet at 13:00 for practical sessions using the DynaFit software.


DetailsTop of pageNext section

University Masaryk University Brno, Czech Republic
College Faculty of Science
Department Institute of Experimental Biology
Term Spring 2014
Dates May 12 - May 16, 2014
Course code IC113
Course title Binding Analysis for Experimental Biologists
Language of instruction English
Guarantor doc. RNDr. Jiri Fajkus, CSc.
Contact Mgr. Ctirad Hofr, Ph.D.
Instructor Petr Kuzmic, Ph.D.
Co-instructor Mgr. Ctirad Hofr, Ph.D.
Grading Pass / Fail (zápočet)
Credits 2
Required courses None
Maximum class size 12
Course format Intensive lecture course with practical computer sessions
Evaluation criteria Active participation during lecture and exercise sessions
Required literature None
Formal discussion groups None


ReferencesTop of pageNext section

1. "Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase"
Kuzmic, P. (1996) Anal. Biochem. 237, 260-273
[ Full Text PDF ]
  • Original publication announcing DYNAFIT.
  • Explains the rationale for numerical methods.


2. "DynaFit - A Software Package for Enzymology"
Kuzmic, P. (2009) Methods Enzymol. 283, 247-280
[ Full Text PDF ]
  • New features in version 4 (2009).
  • Literature references to Differential Evolution, Monte-Carlo confidence intervals, and other important algorithms.


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